Detalles de la búsqueda
1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell;
184(24): 5886-5901.e22, 2021 11 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34822784
2.
Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery.
J Biol Chem;
291(2): 630-9, 2016 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26555268
3.
Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25.
Nucleic Acids Res;
43(14): 7110-21, 2015 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26130716
4.
The structural organization of the N-terminus domain of SopB, a virulence factor of Salmonella, depends on the nature of its protein partners.
Biochim Biophys Acta;
1834(12): 2564-72, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24075929
5.
Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.
J Biol Chem;
287(28): 23283-93, 2012 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22553201
6.
Dimeric α-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors.
J Biol Chem;
287(9): 6725-34, 2012 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-22223648
7.
Advancing structural biology through breakthroughs in AI.
Curr Opin Struct Biol;
80: 102601, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37182397
8.
Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis.
J Am Chem Soc;
133(14): 5363-71, 2011 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21322593
9.
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors.
Bioorg Med Chem;
19(20): 6107-19, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21920761
10.
Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor.
J Neurochem;
111(4): 934-44, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19712060
11.
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists.
Nat Commun;
10(1): 17, 2019 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30604743
12.
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
J Med Chem;
62(1): 207-222, 2019 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29455526
13.
X-ray structure of papaya chitinase reveals the substrate binding mode of glycosyl hydrolase family 19 chitinases.
Biochemistry;
47(32): 8283-91, 2008 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18636748
14.
Crystal structures of two Bordetella pertussis periplasmic receptors contribute to defining a novel pyroglutamic acid binding DctP subfamily.
J Mol Biol;
370(1): 93-106, 2007 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-17499270
15.
X-ray structure of alisporivir in complex with cyclophilin A at 1.5â Å resolution.
Acta Crystallogr F Struct Biol Commun;
74(Pt 9): 583-592, 2018 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30198892
16.
Crystal structure of human Mediator subunit MED23.
Nat Commun;
9(1): 3389, 2018 08 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30140054
17.
Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.
Sci Rep;
8(1): 41, 2018 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29311713
18.
Crystallization and preliminary X-ray diffraction analysis of two extracytoplasmic solute receptors of the DctP family from Bordetella pertussis.
Acta Crystallogr Sect F Struct Biol Cryst Commun;
62(Pt 10): 970-2, 2006 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17012786
19.
Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.
Nat Commun;
4: 1875, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23695669
20.
Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.
J Med Chem;
54(8): 2994-3010, 2011 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21417236